(KMOV.com) -- MoDOT will close Interstate 64 once again this weekend.
Starting Friday at 8 p.m., all lanes and ramps between Hampton Avenue and Forest Park Parkway will be closed.
The work is part of the larget project of constructing a new Tower Grove and Boyle Avenues intersection and replacing four bridges over the interstate.
As part of the closures, crews will be relocating several utilities under the roadway.
The interstate will be reopened by 3 a.m. Monday.