Doctors testing experimental blood clotting drug at Barnes-Jewis -

Doctors testing experimental blood clotting drug at Barnes-Jewish

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ST. LOUIS, Mo. ( – An upcoming drug trial at Barnes-Jewish Hospital aims to help people that arrive to the emergency room with life threatening injuries, but the drug in question has not yet been approved by the FDA.

For trauma patients who arrive at the hospital bleeding to death every second counts.

“What we've learned is bleeding, hemorraghing, [is the] leading cause of death in trauma patients, so anything we can do to decrease bleeding and that will potentially save lives,” said Dr. Grant Bochicchio, Chief of Trauma and Acute and Critical Care Surgery at Washington University.

Dr. Bochicchio is part of the team of Wash-U physicians involved in a research study using the drug Tampiti to improve care for trauma patients.

“This drug has been used for decades and has been found to be extremely safe,” said Dr. Bochicchio.

Tampiti is commonly used to treat hemophellia or extreme menstrual bleeding because it stimulates blood clotting.

“Also in operating rooms every day, it's safety profile is good, we wouldn't be able to do a study like this if there wasn't a good safety profile for this drug,” said Dr. Bochicchio.

Dr. Phillip Spinella is a pediatric critical care physician at Wash-U and has had 12 years of active duty with the U.S. Army, which is also studying the drug’s effectiveness in treating wounded soldiers. Both doctors say side effects, including increased clotting and seizures are rare.

“The way we are dosing this drug and the timing of it, greatly reduces concern of increased clots and the lower dose greatly diminishes the concern for seizures,” said Dr. Spinella.

The trial will begin at Barnes Hospital early next year and will only be used on trauma patients who meet specific criteria. At times the drug may be administered without a patients consent, but there is a way to opt-out of the trial.

To opt-out of the trial call or email the Tampiti trial team at Washington University School of Medicine and request a “Tampiti opt-out” bracelet.

It is recommended that you wear the bracelet at all times.

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