COLUMBIA, Mo. (AP) -- Colt McCoy completed his first 11 passes and produced touchdowns on No. 3 Texas' first three drives, helping to put Missouri away early in a 41-7 victory on Saturday night.
McCoy matched his season best with three touchdown passes, two of them to Jordan Shipley, while Texas' defense blocked a punt for a score in a nearly flawless first half that produced a 35-7 lead.
The Longhorns (7-0, 4-0 Big 12) beat Missouri for the sixth straight time and Blaine Gabbert was held to 84 yards passing and a touchdown before getting pulled late in the third quarter.
The Tigers (4-3, 0-3) have opened conference play with three straight losses for the first time since 2002 and by a combined score of 95-36 although the toughest stretch of the season by far is over with Missouri at Colorado (2-5) next week.
The last two meetings were both essentially over by halftime, with Texas leading 35-3 last year in Austin en route to a 56-31 thrashing. This was Missouri's most lopsided loss in the series since a 65-0 setback in 1932 and worst home loss since a 38-0 loss to Kansas State in the 2002 finale.
A homecoming crowd of 71,004 was silenced early. Thousands were headed home by halftime and the stands less than half-full early in the fourth quarter.
McCoy was 26 for 31 for 269 yards with an interception. Shipley had seven catches for 108 yards, his fourth 100-yard game of the season, with scoring catches of 8 and 13 yards.
Texas is 31-4 against the Big 12 North since 1998 and coach Mack Brown is 6-0 against Missouri, the two-time defending North division champions.
Gabbert was 8 for 16, including a touchdown, before getting pulled late in the third quarter. Gabbert had been hobbled by a sprained right ankle the previous two weeks, but his problems appeared to have more to do with Texas' stifling defense.
McCoy totaled one touchdown pass the previous two games and had been a bit of a question mark this week due to a bruised right thumb. Instead, Texas led 21-0 late in the first quarter.
McCoy opened 9 for 9 for 106 yards and the Longhorns had a 170-1 advantage in total yards before Missouri got anything going.
The Longhorns scored a pair of touchdowns in the final two minutes of the half. McCoy hit Shipley for a 13-yard score and Curtis Brown blocked a punt in the end zone that was recovered by Malcolm Williams.
(Copyright 2009 by The Associated Press. All Rights Reserved.)