COLUMBIA, Mo. (AP) -- Chase Daniel threw three touchdown passes in the first half and Derrick Washington scored three times, helping No. 6 Missouri run up a quick 42-point lead before calling in the reserves in a 52-3 romp over Southeast Missouri on Saturday night.
Missouri (2-0) scored on its first five possessions, Sean Weatherspoon returned an interception for a score and the Tigers ended up three points shy of the school record for first-half scoring against Kansas in 1969.
The first-string offense faced only one third down, averaged 13.3 yards per play in the first quarter and didn't punt until backup quarterback Chase Patton ran an unsuccessful series in the final four minutes of the half.
The Tigers were not above rubbing it in against a lower-division school they last faced in 1936, scoring on a trick play with Daniel's 28-yard pass off a lateral pass from Jeremy Maclin making it 21-0 late in the first quarter. Southeast Missouri State (1-1) has lost its last three games against BCS competition by a combined 174-13, also getting steamrolled by Cincinnati last season and Arkansas in 2006.
Daniel was 16-for-17 for 245 yards, the lone misfire followed by 14 straight completions -- one off the school record he shares with Kent Kiefer (1990). None of the drives lasted three minutes.
Washington had 67 yards on eight carries and scored on a pair of 5-yard runs and a 28-yard reception on the trick play, giving him five touchdowns in his first two weeks as the starting tailback. Maclin, who sprained his left ankle in the fourth quarter of a 52-42 opening victory over Illinois, scored on a 3-yard reception and had a 29-yard punt return.
Weatherspoon became the first player in school history to score on an interception in consecutive weeks and Ziggy Hood gave Missouri blocked extra-point kicks in its first two games.
Southeast Missouri, an FCS team playing up in class for a $250,000 payday, didn't get a first down until its third possession. The Redhawks came up empty on two effective drives in the first half, with Hood blocking a 28-yard field goal attempt and Doug Spada missing a 28-yard field goal attempt, before Spada broke the shutout on a 41-yarder early in the fourth.
The second half was notable because Missouri started freshman quarterback Blaine Gabbert, one of the top recruits in the nation last year. The school had been debating whether to redshirt Gabbert.
Missouri is 8-0 against teams from the Championship Subdivision, with a total score of 214-33.
(Copyright 2008 by The Associated Press. All Rights Reserved.)