Louisville earned the top overall seed in the NCAA tournament Sunday, a process complicated by the topsy-turvy regular season and another round of weekend upsets.
The selection committee had its work cut out after five teams swapped the No. 1 ranking in The Associated Press rankings, capped by West Coast Conference champion Gonzaga (30-2) moving to the lead spot for the first time in school history.
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But it was No. 4 Louisville (29-5) that got the overall top seed after sharing the Big East regular-season title, then pulling off a stunning comeback to beat Syracuse in the conference tournament final.
The other regional top seeds are Gonzaga, Indiana, and Kansas.
The Louisville Cardinals have shown that they are comfortable being front-runners in their season-long quest to go further than last year's Final Four appearance.
Now, they enter the NCAA tournament as the overall No 1 seed. A familiar position for this squad, which was ranked No. 2 to start the season and was the preseason favorite to win the Big East.
Last year Louisville got hot during a surprising run in the Big East tournament and continued rolling to the Final Four.
Not this year.
The Cardinals (29-5) are on a 10-game winning streak and have captured their second straight Big East championship. Louisville opens play Thursday at Rupp Arena, about 75 miles east of its campus, against the winner of Tuesday's game between North Carolina A&T and Liberty.
CBS Sports' Dennis Dodd writes that the Kansas Jayhawks are also well positioned as a No. 1 seed to make a run deep into the tournament.
"Their style fits March," Dodd wrote. "If the Jayhawks continue to funnel everything to the middle where 7-foot Jeff Withey awaits on defense, that's a hell of a strategy. After that, well, the offense tends to become a bit easier this time of year."
Indiana was ranked No. 1 in the preseason in both the Associated Press and Coaches polls, picked to win the Big Ten and generally considered among the favorites to win the national championship, the Hoosiers' sixth and first since 1987. IU has spent the past four months mostly living up to expectations.